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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2c27c09bd64e0c75b6b43f32943e3c4d75f38c65b3820f18d67831504d3f3b0' 
  AND token = 'J8dTpRikqansA57agj16cWQqprK6hDrsRo6xtNvEoe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}