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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e3cc4c64acf0e78b038e1ae3b2bf02dc34b6439349233302bcfffacdb10d154' 
  AND token = 'uVO1Lp2yQ4Nm11OIv7gngDTZw2T/6kGUwN+OXKKWDNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}