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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4118e615405aa88b2d8097c3c6219bc742690e5516efd0c5f693b6b88c644ae5' 
  AND token = 'xejI8DYrdSsFYpmZzEcQi3E1IlRyHZwKYIkt66ErLjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}