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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4f4f3f7883687f5eb92c14a1f37cc075941035cf09986d1432e6c7a69e5467e' 
  AND token = 'gW3s42XlI7V1xzb/dV0P2afTulr9b8DAmiIDD8XO7/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}