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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a59233552867590d316046d6845acc2685d50c40028fdb157a195bb8878cecf' 
  AND token = 'Sl+YPPqo5kCLa5akt+AC3xVRdB9Nrm9tdFahSiOc3J8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}