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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49676a0e80a97230830708914d9c62799d5610ebf38e7522a0c3eb64c474af48' 
  AND token = 'ugi9tvMbfBQ6/kG9uRJ9jcdx3S7ufkCs0R8IKkf0uL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}