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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b728a9d3aaf57187ef4ce85a0b5371bf791d42558855b18ba354921d27624a48' 
  AND token = 'oTUVXEM72iSn/nJW3J9Ev6/nbgHH/N1S3QH9jWcWGeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}