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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b6a9cffa80658ae189adeb429df40617dc32c6086760b8191fedb818c9052b1' 
  AND token = 'YSTyrr4OkA3//LYmjCOcVAG86bxN5EA1OPTKYIQxrHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}