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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a27e5f0f6ac2f1b168176775508a475acd1be33d3cf261418ae0eca86e07581' 
  AND token = '2UWE8dSvu0YREicw5mhIzGr8e4rYvHL1QkZ4jlrJhhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}