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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e03243fda0f0a88379fcd53a26147ab6ab338f2a03730b1165ecd2d2c47a3d9' 
  AND token = 'PvRRlZZvUVFXLskvU3GRT5ujXbjVItz5RzJIOb+iEDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}