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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b58b8efd69357b382a50120ed212cbd6170faab7358fca55e03afc1fdd3b5f08' 
  AND token = 'd9zun/G0iRb78b+UQJVC9Hs4zrSlrMB+ZY31OyhzTvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}