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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8aa84ea1e67704335e0d1bb6c7d98d6f77db34c99bff20b6c4e797b6d083a8' 
  AND token = 'CWfc3L59E7qy3Ky6U/aO58y2KENnOrA1e5qM+m8Q1V0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}