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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f160cb25a206542678200e0df43ad50979ea642d15c2faa7942f1e1872c3c3c3' 
  AND token = 'QrQr/ak1KnJ0rb4aP5ZXnqvqCHImkTqnt8clel5smos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}