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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd8a9a6a1c87a661c246b5862866b7f06000b2173a1502dfbf761524136f7120' 
  AND token = 'pI6Cnagbo1MGKxW0LL6WJNjmRbbQGMcu9+32Z9kvMhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}