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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '417f13350802409706b3e6f0298344f3bdf6bdf3a2ab34c991ce2c9bb942f6a5' 
  AND token = 'ubYeo0IYrHazRsovSxWDRokCVmP1RvuAjcMjAp+aaEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}