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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cc92e9076246b31f3f2a920087e8a1f14bd9f99fe8671c47889bf726106e500' 
  AND token = 'AiyPI9frTMXXDoQPLk3WYdmk3mOF5jk6zb9Fqt42jPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}