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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80cc437c015d0bc1f341fec8c0aa47fbff4d52dac46c6606d205283d175c97a0' 
  AND token = '9cBpWNESqdBSMCyTZ4eaR9X4KwesPEiuE2c46mcvCzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}