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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6fe493917df8383102e07d9d692377a9c2292faaa36fdadc8e9f6c9389f3e96' 
  AND token = 'doWifcDkr5Vzk1APYgf0FKhnBo4T6qtqKdMYxJPDm2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}