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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da19bb12c23052dbdebfe21959d472c5bbc5e99871407f556719c3aa80d6ab67' 
  AND token = '41S0/V1U9OOmjOSs2UW8wu65gsHyTktwNzMrOi4RIdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}