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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed70797b9c4ae699375de2bf00e8f317655f7393a07f8b0018d19da605b6bd0d' 
  AND token = 'u6iA91Bj17NSsA5fSvpPkMwB/TJePGhDkgohMH41Bh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}