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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce0b8940ed2fc4c2c6cb45286e01145e29fe204e49206a724acdb6f99161c680' 
  AND token = 'ZPD+Uuxdg7zZKxV/Oj7QYnbGuG6hmSS8ADXOwOE5134=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}