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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e99d9bfb9ad3b176cc3c18045f7b47d02b12f1a36f6726b79f84e8103e20210' 
  AND token = 'l7CS9vhM+hJ6Ho2frOAQ2T5m2XDHXxpbwoZyYI/1/bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}