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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6e9fe174d3faa03c660acb2041be37727528502e0261a9388dde8b0c7ea1cfa' 
  AND token = '+txSvJ6NyEUf/yTKmYpGuPG6se8JfB3r01uBD4h29EI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}