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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d8ad0666bf2c838e49b65a3790c3cc381facb82c23d28cc0f3d3b264bb36fc' 
  AND token = 'iZX0R+9XsAX7izAjSdN+MzQx8Y7FgqQWlkszYKkgURI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}