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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a488b973b24a7c3b6aa6efeb5e266a0676b3396378288f83e6642be900c3a570' 
  AND token = 'nGSiGjstbbHW2m/oHjKxtBr2PG1NAOBxlPF/08G7Bbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}