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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2f20e4612e6510b7b33a412ed5b8d44cf99cb00df0067edbf9eacff6b421b7b' 
  AND token = 'Obl+IvmMrSV8i9QizSNF1Ypi9IVIkO70fix7owWMC4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}