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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9fd71af7e07cd5dbd5ac04a72b332f5541ce10131bf14a68d2776e755f4c710' 
  AND token = 'QE0vNuAX3N4Nsub/zCQqmHt6KG1KC1rYKZH9VEYN2GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}