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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53faa0536a87073728e08e445a294599c0ec26498cf439049d8c18033854b788' 
  AND token = '6sTVDIeeoIE0xTjexewjdOn4brRwnmVb2gakrHwpcSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}