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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e9b28ca8c9b9d3fad6e7122f9d72f5dc3672f5a8116b54fdb5e2ce279519e7' 
  AND token = 'Gnd6sRb2OAS04Tzi2sCI+IC1MFz3C+Kg9cum9sDJmsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}