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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5854a82e53681b9caab2aa41aa0e9f9a27e33f3b80c71c963e5c06f9175bf9f' 
  AND token = 'QX9+V8UIVTl8nYNbEcx56Q0iCAsXHY/6gM1IN/XeqrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}