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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f836db25ddaf3421d555b60cfa3255de56f7f7ac1b8d070e9b445ed6b2701a' 
  AND token = '0DXHQI5lxCh3WHFZ11Bh+zYoOBGOw2oFuoiBzE/eyOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}