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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7370b0dd9935baa23be026106f5c0678dc8acfccd12d4d2053e7b9507c1bcf78' 
  AND token = 'OclQePm7Kp0bnKEl9Tbdyy1CS/BK2lA1Y+SP7/SJtdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}