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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '448afa32c31eb97764baf37010574a2694cf59dd08fecb301c8e739f7517053d' 
  AND token = '1kQ7qGl9xoLGvDD+BlyC2RqyAvLulUy6pwkgqnqO6p0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}