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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f7e4d126ffa48a1edf217fad7cb70f5014a65db2de4be8b14f2085dab67a5e9' 
  AND token = 'wD3MqjMd0VBMBIeVzRCMhlDY9ONT9u+n3DHDTi9l5LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}