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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821ace0da6c5e808f7eb50aef3705f0b652ddceb9a689271ec84c2e1f0cbe498' 
  AND token = '5Yip8MjHK+bpmh4cGD17fEsH5yVw40WM/TeVh9gKGhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}