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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '157a81c73c5cfc0117b9feb2c4d925e0df8cc6502571007d081aa372227c15ff' 
  AND token = 'j8DoJC35uG4eravKWN4DIP5XWXWDo+nXPB3BUNiXFSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}