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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '000637e306c182b3fc8d376ce3bce347d93443c7a1bb9c7ea186a732c11c3dfb' 
  AND token = 'oWFhzKwSbiq8X6hxYiBopqsJeLJeJF0NDLiAQjbUcs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}