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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a4efca459c55d50482a8a7a137d05781bc42a3be6c941358f566afdc571d3f8' 
  AND token = 'yvGkzPp4wzUZVm95lJV39CJetJAzcfIL0MZAR0pp6jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}