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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2be70dc3bc79d7106e616c39be79fca05c5352ce6ba635ef8b731edfceb5d2d4' 
  AND token = 'NYBPecaLtBoVmBCedqc8V1L2xfCAUEELyYqvbjtgD3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}