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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1188fa65c728d33c5cc574842d6653c8f946d2eaa9ac0986b5b0edba8b5283a' 
  AND token = 'RxtoipVS+uB6EbLbDHZTtRDdm+6f7OvKmi6U4oNSb/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}