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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6590299f2cc928b9d79e5eda6a7de51bff2e58a270ebb379b199f85a0531c1f' 
  AND token = 'MDgCKAQwBeRpXh99mJYFU5gpg5kiiDIoW8PnAkgFJPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}