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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aa2410dfe7316805da7fbaeb912d4be594fc256942b5d8bf53e011665b1bdde' 
  AND token = '72+kflchDnXfkn8da2TpkUlYrf/Pr2pJKZFNmpcK9RE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}