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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '770c09c6aa2ed821bf48febe9d54197aad2a33626ecbfea73c5be53ab4a6fa99' 
  AND token = 'p25QPz+DI9zoKBYiNadl5NNP38tc3GdPsGw9XnuEtOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}