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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0af924b8e5336e8d2ebe09ba0a817c1dacff13e425a42698454e22348aaa425' 
  AND token = '9v5nUkF6izAH6mrNBc/GhDLg7mzrBLD4XlMZ4dkVVEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}