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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fd72f39aa80500612d32c4165b3a85e9dbb9e29e8534ee1ffe3af7fff4dea85' 
  AND token = 'ibrrOcOKu4B9PG2+McaB8IGjioI45KHtzmZ+3gJOL2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}