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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ddb000f5db4316c92d777b705327da52f1cb2aadc87ae5d2f3fccfd62006f0f' 
  AND token = '7KDgI9bEdBOgUY4LfQag9YBUs3GvIRTmxg9hQ0CA23Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}