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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caafeb29844b6e0d3f2e5684822f65d34d1efa9000515a4bf5ac204adfe43342' 
  AND token = 'fAcrQbHtnLr2uwvpi7f9BIUa6vrpFWxxVa/NLDSvKn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}