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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4bc0a967c3b942e437a721da76e45fd5ff91bc5b638088317b46d53e6f069f4' 
  AND token = 'CG9MVVucqMePLL6mnDEBuUt53UrEDotNGkN1oUfL2I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}