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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2b4c017f8821b807092788a6de91f39ec89074daece6cdb48e0b13db84df7a3' 
  AND token = 'wtJz2iaUV2Yn6uCNkUG2peU0SdyecyzM7xC4HFMwJc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}