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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b8edbb695fd2da7655728439da8fd9ffeab5e79fcd9d1147eb3c40a64241e8' 
  AND token = '+xY1vxWv0oG6KPUJSN0saMaJj9VUWUEijstdMx3t9U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}